Some health problems affect our personality. This problem can be mental as well as physical. Due to this, there is a change in personality. This change is also responsible for borderline personality disorder. Recent research suggests that due to this disorder, brain activity becomes absent (Mental Disorder affect Brain Activity).
What is research (Research on Brain Activity)
Researchers from the City College of New York, Columbia University and the New York State Psychiatric Institute conducted research on brain activity. Researchers have identified one brain region, the rostro-medial prefrontal cortex. The rostro-medial prefrontal becomes especially active when people are strongly rejected by others.
negative effects of social rejection
It reacts differently to social rejection in individuals with Borderline Personality Disorder. This area is typically more active during episodes of rejection. It remains inactive in people with borderline personality disorder (BPD). It shows great sensitivity to rejection and emotional instability.
What is Borderline Personality Disorder
Anyone who is socially ostracized, that is, rejected, is more likely to develop borderline personality disorder. Its effect is more on the nervous system. This makes the function ambiguous. The research aimed to explore the role of social rejection in various mental health disorders such as PTSD (Post-traumatic stress disorder), depression and social anxiety.
Borderline personality disorder may arise from failure to maintain or upregulate the activity of the rostromedial prefrontal cortex, a key node of the mentalization network. In this, being rejected has an effect on brain activity. This increases the risk of rejection.
Conclusion of Research
Cyberball functional magnetic resonance imaging modification was tested on 23 women with socially rejected borderline personality disorder and 22 healthy participants. The researchers tested group differences in whole-brain reactivity. They found that the brain activity of women experiencing BPD was affected. It remains inactive in individuals with BPD. This passivity may reflect the greater sensitivity to rejection of people with BPD.

Cause of More Emotions
Deactivation in the rostro-medial prefrontal cortex during rejection may provide specific cues. This may explain why people with BPD are more sensitive to rejection and more distressed or sad. Knowing why individuals with this debilitating and high-risk disorder experience emotional distress due to rejection will aid in the treatment of people with BPD.
Will help in treatment (Borderline Personality Disorder Treatment)
The research findings could lead to future diagnosis and treatment for mental health disorders, especially BPD (Borderline Personality Disorder). Also the role of social rejection in other mental health disorders may be investigated. When rejected, a major part of the brain, the rostro-medial prefrontal cortex, does not show activity.

effects on mental and emotional state
Rostro-medial prefrontal activity indicates that something is wrong in the environment. This brain activity may activate an effort to restore and maintain close social relationships in order to survive and thrive. This area of the brain is also activated when humans try to understand other people’s behavior. It understands based on the mental and emotional state of the other person.
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